Follicular lymphoma (FL)

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Follicular lymphoma (FL)

The patients most often present widespead disease at diagnosis, with nodal and extranodal (bone marrow) involvement. Peripheral blood involvement is detectable by light microscopy in approximately 10% of the cases, but the majority of cases can be shown to have circulating malignant cells by sensitive molecular genetic methods. The disease usually runs an indolent course. Grade 3 FL may be char...

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indolent lymphoma 309 QUALITY OF LIFE MEASURES IN ‘ASYMPTOMATIC’ PATIENTS WITH FOLLICULAR LYMPHOMA (FL) AT PRESENTATION

K. Ardeshna, W. Qian, P. Smith, L. Stevens, C. Pocock, M. Dyer, J. Davies, D. Cunningham, A. Kruger, D. Linch Department of Haematology, University College London Hospital, London, United Kingdom, On Behalf of UK NCRI Lymphoma Clinical Studies Group, MRC, Clinical Trials Unit, Oxford, United Kingdom, CR UK and UCL, Cancer Trials Center, London, United Kingdom, East Kent Hospitals, Canterbury, U...

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Radiotherapy for stage I/II follicular lymphoma (FL): is it time for a re-appraisal?

AIM Almost 30% of follicular lymphomas (FL) present with stage I-II disease. Although the standard-of-care consists of involved-field radiotherapy (IFRT), approximately half of patients relapse usually outside the primary irradiation field. Systemic immunotherapy with rituximab (R), with or without IFRT, could reduce distant recurrences leading to a better outcome. Therefore, we compared the ef...

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Lymphoma cell line (FL-18) and Epstein-Barr virus-carrying cell line (FL-18-EB) obtained from a patient with follicular lymphoma: monoclonal derivation and different properties.

A novel cell line, FL-18, was established from the pleural effusion of a patient with follicular small cleaved cell lymphoma. At the same time, an Epstein-Barr virus (EBV) nuclear antigen (EBNA)-positive cell line, FL-18-EB, was established from the EBV-infected culture of the same pleural effusion cells. Both cell lines had the same monoclonal surface immunoglobulin (IgG kappa), and they had t...

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Follicular Lymphoma

The article entitled “Renal Infiltration of Follicular Lymphoma”, written by Petkovic et al. and published in one of the recent issues of your journal, was quite interesting [1]. Here we would like to emphasize some relevant points. Extranodal disease is relatively common; any organ may be involved. The most common sites of extranodal disease include the bone marrow, skin, gastrointestinal trac...

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ژورنال

عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology

سال: 2011

ISSN: 1768-3262

DOI: 10.4267/2042/38322